Viagra Choosing the right ED pill can be intimidating. Often, these are prescribed for chest pain called angina. These PDE5 inhibitors may cause headache, flushing, drop in blood pressure, or other adverse effects. This boosts blood flow and helps you get an erection from sexual activity. Make sure to get an estimate of when you can expect your prescription in the mail. In addition, consider the information below. Popular ED medications found online include: Viagra sildenafil : As the first FDA-approved PDE5 inhibitor for ED, sildenafil is taken 30 minutes to four hours before sexual intercourse to help achieve and maintain an erection.Dosage. The dose of Cialis you need will depend on whether you’re taking it daily or as needed. Daily doses are often between and 5 milligrams (mg). The as-needed dose is usually 10 mg but can range from 5–20 mg. The typicaldose of Viagra is 50 mg. However, the dosage can range from 25– mg. Cialis lasts up to 36 hours in the body, while Viagra lasts 4–6 hours in the body. Both are taken 30 minutes before sex. Cialis can cause limb pain, while Viagra can cause vision change, rash. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide.