Take vardenafil exactly as directed. The most common symptoms of erectile dysfunction include difficulty achieving or maintaining an erection and reduced sexual desire. If you ever need emergency medical treatment for a heart problem, the health care providers who treat you will need to know when you last took vardenafil. Other CYP3A4 inhibitors: Although specific interactions have not been studied, other CYP3A4 inhibitors, including grapefruit juice would likely increase vardenafil exposure. WARNINGS Cardiovascular effects General: Physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity.Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Vardenafil does not cure erectile dysfunction or increase sexual desire. Vardenafil does not prevent pregnancy or the spread of sexually. It may also be used to treat the enlargement of the prostate gland. This drug is slightly more popular than comparable drugs. It is available in both brand and generic versions. Cialis is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. It is a PDE5 inhibitor. It is taken by mouth. Medical use. Vardenafil’s indications and.