From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. You should take tadalafil one time a day. If you are taking tadalafil to treat erectile dysfunction, follow your doctor’s directions and the guidelines in this paragraph. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Counterfeit medicines can be very dangerous. John’s wort.heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Common tadalafil side effects may include: headache; flushing (warmth, redness, or tingly feeling); nausea, upset stomach; stuffy nose; or. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side. Cialis is a medication approved by the Food and Drug Administration (FDA) often used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) in those assigned male at birth. Roman is a telehealth prescription service and online pharmacy that provides prescription Cialis for ED and a host of other conditions, like hair loss, cold sores, and premature ejaculation. When.