You could get dizzy, faint or have a heart attack or stroke. Because they are the same class of medications, they have similar side effects and effectiveness. Tadalafil will make these symptoms less severe and reduce the chance that prostate surgery will be needed. Erectile dysfunction medications require a prescription from a licensed provider. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. · Generic tadalafil tablets, many of which are symmetrical, are film-coated (brand Cialis is film-coated too). Splitting these tablets will destroy the film-coating. Aside from the two reasons above, other reasons exist for the recommendation not to split the tablets. They include: Split Cialis tablets have not been tested for safety or efficacy. stockcam / Getty Images. What is generic Cialis? Generic Cialis is called tadalafil, which is the active ingredient in Cialis. Cialis is Food and Drug Administration (FDA) approved to treat. Cialis is available as the generic drug tadalafil. A generic drug is an exact copy of the active drug in a brand-name medication and is considered just as safe and effective.